KMID : 0387719940050010001
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Korean Journal of Blood Transfusion 1994 Volume.5 No. 1 p.1 ~ p.7
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Peripheral Blood Stem Cell Collection with an Automated Blood Cell Separator
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Abstract
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Peripheral blood stem cells (PBSC) were collected for autologous transplantation for the first time in Korea with Fenwal CS-3000 Plus blood cell separator. Twenty-nine procedures were performed for 7 patients without any incidents. GM-CSF (400ug)
was
administered daily for 5 days before PBSC collection and the collections were performed 3-6 successive days. A total of 3.5-11.4¡¿10E9 mononuclear cells (MNCs) were collected from 7,000mL blood processed per procedure. The number of MNCs
collected
was
mainly dependent on the concentration of MNCs in patient's blood (r=0.68, p<0.01). We concluded that the PBSC transplantation program could be set up without difficulty in Korea since the Fenwal CS-3000 Plus blood cell separator is already
available in
many institutions and the procedure used in this study is easy to follow.
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KEYWORD
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